ANÁLISIS PRIMARIO DE ZEOLITA (CLINOPTILOLITA)

ANÁLISIS PRIMARIO DE ZEOLITA (CLINOPTILOLITA)

A. Propiedades Físicas

Color: Material de color grisáceo claro, con tonalidades blancas. Punto de fusión: p.f =985° - 1270 °C Peso especifico: p = 0.98 – 1.16 gr/cm3 Capacidad adsorptiva de agua: 24 – 32% P/P Solución acuosa: a) pH=6.58 – 7.14 b) Conductividad C= 9.14 Microsiemens (a 24.7°C)

B. Difracción de Rayos X El Difractograma de Rayos X, revela fundamentalmente la presencia de Clinoptilolita (72%): Na 1.40Ca 0.10 K 0.30 Mg 0.50 [Al2O4 .(SiO2 ) 9.6 ].5H2O o bien: (Na, Ca, Mg)6 (Si, Al) 36 O 72 .20H 2 O Otros minerales presentes y detectados (8.4%) por DRX: Dolomita: [Ca(Mg,Fe)]CO3, Montmorilonita, Cuarzo; SiO2 Condiciones del Barrido DRX: Anodo Cu, λ1=1.54060 λ2=1.54443 Step size: 0.030 cps at 20:4000 Theta Su patrón de Difracción presenta la siguiente relación distancia interplanar (Å) Vs Intensidad relativa. [ d(Å) 8.92 7.83 6.78 5.24 5.11 4.64 3.976 ] [I/I0 + 100 32 20 ..... 27 28.5 30 .... + 95. ] C. Porosidad Radio Poro

(ypFe>K

ANÁLISIS QUÍMICO ELEMENTAL % P/P __________________________________________________________________________ Me +n O ......................ZNT -17 ..............................[[H + ] 17-C ...........................Ca,Mg,K .................................. HORIZONTE C ..............30 Tratamientos .....................Modificada __________________________________________________________________________ SiO 2 ............................64.20......................................... 70.16................................. 62.73 Al2 O3...........................12.80 .........................................10.28 .................................12.93 Fe2 O3 .........................2.30 ............................................0.27.................................... 1.75 MgO............................. 0.54 ............................................0.13 ....................................1.26 CaO.............................. 4.80 ............................................1.02 ....................................4.68 Na2O ............................1.60 ............................................0.74.................................... 0.68 2O ..............................1.96.............................................. 0.92.................................... 2.87 P2O5.............................1.10............................................ 0.92.................................... 2.87 PXC .............................10.70............................................ 9.86 ..................................13.10 ________________________________________________________________________

*Análisis realizado por el Instituto de Ciencias de la Benemérita Universidad Autónoma de Puebla.

Doctors Comment Magic in Our Midst: Zeolite and Humic Acid Dr. Howard Peiper, N.D., nominated for a Pulitzer Prize, has written many best-selling books on nutrition and natural health including, “Zeolite, Nature’s Heavy Metal Detoxifier” and Viral Immunity with Humic Acid”.

Zeolite is the Super Detoxifier Toxic chemicals, including poisonous heavy metals like mercury, lead, arsenic, and cadmium, are the worst problem faced by all life as we know it. We literally live in a chemical soup. The chemicals come into our bodies through the food we eat, the water we drink, and the very air we breathe. This situation actually threatens our survival. Until recently, the only sure way to remove the most destructive heavy metals and toxins from our bodies was through I.V. chelation, a process both invasive and horrendously expensive. And even if we spent hundreds of hours and thousand of dollars on chelation treatments, the toxins would start going right back in with our next breath, our next meal, our next beverage. But the solution is at hand. It’s a miracle mineral called zeolite, and it is perhaps one of the most important substances on Earth today.

What is Zeolite? Zeolite is part of a group of minerals with a four-sided honeycomb structure and, rare among minerals, a negative magnetic charge. The effect of the structure and the magnetic charge is that zeolites attract heavy metals and toxins to it and simply engulfs them. The toxins “check in” and they can’t “check out.” Then the zeolite carries them safely and harmlessly out of the body through normal digestion. Because of its effect on toxins, zeolite has been used as a supplement in China for more than 900 years. In the West, it has been used by industry for various tasks, including clearing up water pollution and as a food additive for animals. The form of zeolite I recommend (there are many naturally occurring zeolites) is called ‘clinoptilolite,’ and it is this type of zeolite (in a powder form) that has been studied for its effect in human nutrition.

Medical Uses of Zeolite

Studies have shown that zeolite has a high affinity for trapping lead, cadmium, arsenic, mercury and other potentially harmful metals. Through the process of cation exchange, zeolite can lower overall heavy metal exposure in individuals. This would have a dramatic effect in the risk reduction of certain cancers and heart disease. Zeolite buffers the system towards slight alkalinity by establishing pH levels of 7.35 to 7.45 which is the optimum pH for the body. The body’s pH level influences both immunity and brain function. An acid blood pH (7.34 or lower) creates a precondition for cancer. In an acid environment, brain cell function can also be impaired, causing depression, anxiety, stupor, paranoia, delusions or hallucinations. Zeolite is a unique antioxidant. A traditional antioxidant works by absorbing excess free radicals into its system because it has an impaired electron. In contrast, zeolite traps free radicals in its complex structure, inactivating and eliminating them.

Other benefits from taking zeolite are: * Stops acute and chronic diarrhea * Raises the body’s antioxidant levels * Binds mycotoxins, forming stable complexes * Reduces side effects of chemotherapy/radiation * Stabilizes and regulates immune system

Humic Acid is the Anti-Viral Answer Viruses. Those enigmatic, perplexing and often lethal microbes cause a vast number of human illnesses from the common cold to epidemic diseases. New and changing viruses are appearing at an all too alarming rate and we need an effective way to control their influence on our body.

Referred to as the “missing link” to optimum health and nutrition by leading scientists throughout the world, humic acid is a health miracle .Medical studies now show that it has the ability to significantly change our life for the better. It is so safe, powerful and effective that healers around the world have used it for hundreds of years with amazing results. In agriculture, there are many studies that point to a pattern of serious deficiency of humic acid to commercial livestock. When the deficiency is alleviated, phenomenal results are achieved, including resistance to disease, increased growth, and improved general health. Similarly, human dietary supplementation with humic acid is bringing about life changing results for so many!

So what exactly is this miraculous substance? Scientists have most appropriately referred it to as the Anti-Viral Answer. Humic acid is the smallest, most complex, most highly refined naturally occurring water-soluble substance on Earth. Tiny amounts remarkably transform the molecular structure of water, making it intensely more active and penetrating. Humic acid then assists water in its job of dissolving and transporting. It helps carry nutrients into the cell and waste products away from the cell, while also helping to neutralize toxins and invaders. Humic acid has the dramatic ability to even penetrate deadly ultramicroscopic viruses. Viruses are super small, and live deep inside the cells of plants, animals and humans. Viruses even live inside other microscopic disease causing organisms, where they “hitch-a-ride.” Viruses encapsulate themselves within an impenetrable protein barrier where defense mechanisms cannot get them. Humic acid puts a coating around the viruses so the viruses are not able to adhere to a healthy cell, therefore preventing the viruses from reproducing. The agents for this are called Viral Fusion Inhibitors (through a special proprietary process, humic acid is specially treated and sterilized. Humic acid with Viral Fusion Inhibitors is the only kind I recommend.) The viruses are then vulnerable to attack by the immune system. Yet this is only the beginning, humic acid also has the amazing ability to alert the immune system to the virus or disease invader and to regulate and give strength to the immune system.

The Scientifically proven Micronized Zeolite Zeolite is a breakthrough supplement that works at the cellular level by trapping heavy metals and toxins and safely removing them from the body. Zeolite is also very effective in removing radiation, as shown in the cleanup after the Chernobyl nuclear accident. The people showed a 30% reduction in radioactive isotopes after the very first application of Zeolite! Continued use shows increased benefits. The actual Clinoptilolite Zeolite molecule is shaped like a honeycomb and carries a natural negative (-) charge. When this type of Zeolite is ingested into the body all of the positively charged (+) heavy metals, toxins, and harmful chemicals bond with the zeolite and are flushed out through the urine within 6-8 hours. Using Zeolite for Natural Chelation Therapy is 100% Safe and 100% Effective!

Why our is Zeolite best?

ZEO NRG ZEO Health NCD (ETS) Force LTD. Zeolite

Zeolite Purity Click Here for the Lab reports

94%

68%

48%

48%

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NO

YES

YES

A zeolite can be mined with many impurities.

Does it Contains Mold Click Here for the Lab Reports

Water is often used in the zeolite mining process. If

the zeolite isn't processed properly, mold can grow.

Company Focus on Zeolite Many companies focus on a variety of products and are not zeolite specialist. Make sure that your zeolite supplement manufacturer knows zeolite and has a zeolite expert on staff.

YES

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YES

YES

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YES

YES

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NO

Is the Zeolite Micronized? Milling zeolite will produce a rough gritty powder. Milled zeolite used in a supplement usually means that the manufacturer did very little in the way of processing the zeolite powder and in turn makes a very inefficient supplement product. Micronization is a more expensive process and while it doesn’t guarantee that the manufacturer took all the processing steps to ensure a quality zeolite supplement, it shows more effort than the bare minimum.

Is the Zeolite mined specifically for human consumption? Zeolite is a family of minerals but clinoptinolite is the only member of this family that is found to be safe for consumption.

Zeolite purity can vary, sometimes a product label zeolite could be made up of as little as 45% actual zeolite. The other 55% could be made up of elements that could be toxic if ingested. This is a precaution that many zeolite mines don’t think of because they are geared toward the commercial applications of zeolite.

Meets FDA minimum requirements for dietary Supplement The FDA requires all supplements to abide by a set of label standards. This ensures that the customer can see the componenets of the supplement and easily compare with competitors. As you can see, many zeolite manufacturer are not in complience with the most basic requirement for a supplement manufacturer.

Original Zeolite Supplement Pioneer

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ESTUDIO TECNICO Zeolitas naturales micronizadas Suplemento alimenticio, 100% natural, con alto poder antioxidante y habilidad anticancerígena y antimetástasis Radicales libres, enfermedades degenerativas, antioxidantes Los suplementos alimenticios, sobre todo los de origen 100% natural, son cada vez más populares en el mundo occidental. En 1998, en Estados Unidos, más de US$ 12 mil millones en suplementos alimenticios fueron comprados por los consumidores. La necesidad de soluciones alternativas está creciendo en la población mundial, especialmente en lo que respecta al cáncer. En todo el mundo, las inversiones en investigación científica sobre productos de medicina alternativa, especialmente en lo que respecta a productos naturales, están creciendo en forma importante constantemente. La investigación organizada y científica en medicina alternativa ha crecido en los últimos años y ya se cuenta con mucha evidencia concreta sobre los mecanismos de acción y beneficios de algunos productos naturales. Las zeolitas naturales se usan desde los años 60 del siglo pasado como aditivos en alimentación animal, para el control de las toxinas y para mejorar las utilidades del negocio de producción animal, ya que mejoran la eficiencia de conversión alimenticia y disminuyen notablemente la mortalidad en los planteles industriales. Los productores e investigadores en producción animal comenzaron a notar que, cuando se adicionaban zeolitas naturales molidas a los piensos, también se notaba un aumento en el estado de salud general de los animales (muy pocas enfermedades) y, cuando se hicieron mediciones, se constató un elevado sistema inmunológico de los animales. También se notó que las enfermedades degenerativas en los animales no aparecían o disminuían notablemente. Este fue el comienzo de la idea de usar las zeolitas naturales en alimentación humana, aunque la clinoptilolita ha sido usada por más de 800 años en medicina tradicional para mejorar la salud en general en India, China, Rusia y en casi todas partes de Asia. Las experiencias comenzaron a los finales de los años 80 en el ex área socialista (principalmente Croacia y Rusia) y Cuba. Por cierto, el producto a usar en los seres humanos debe ser un producto mucho más activo, es decir, más puro y más fino. Es así como en la actualidad uno de los productos más prometedores, y que ya cuenta con respaldo científico fuerte en la lucha contra el cáncer y otras enfermedades degenerativas, lo constituyen las zeolitas naturales micronizadas. En lo que respecta al cáncer, las zeolitas naturales micronizadas, a través de una molienda especial, han demostrado una habilidad anticancerígena y antimetástasis en

pruebas in vitro e in vivo, tanto en animales (perros, ratas, etc.) como en seres humanos. Hay miles de experiencias en Croacia y Estados Unidos, principalmente. Existen varias publicaciones en revistas especializadas que muestran resultados concluyentes al respecto. La investigación científica efectuada hasta ahora, principalmente en Croacia, Rusia, Estados Unidos, Cuba e Inglaterra ha demostrado el fuerte poder antioxidante que poseen las zeolitas naturales micronizadas. La capacidad antioxidante de las zeolitas naturales micronizadas sobrepasa largamente a otros productos antioxidantes de reconocida capacidad, como el chocolate, pepitas de uva, vino tinto, la mayor parte de las verduras y frutas (que contienen las vitaminas E y C, y los elementos selenio, calcio, magnesio, etc.). Solo superado por el descubrimiento del ADN, se considera el descubrimiento del papel que juegan los radicales libres en las enfermedades degenerativas como el segundo descubrimiento más importante en la historia de la Medicina. Los radicales libres son una de las causas del envejecimiento así como de unas 60 enfermedades degenerativas crónicas, que incluyen ataques al corazón, artritis, cáncer, cataratas, Alzheimer, Parkinson, diabetes, presión alta (colesterol), várices, reumatismo, stress, flebitis, hemorroides y senilidad. El cuerpo produce radicales libres durante los procesos metabólicos. Los radicales libres son básicamente átomos o moléculas que poseen uno o más electrones desapareados en su órbita más externa. Pueden tener cualquier carga o, inclusive, ser neutros. Son altamente reactivos, ya que buscan alcanzar el equilibrio perdido de su órbita electrónica más externa ya sea donando o “robando” electrones de átomos o moléculas. Cuando lo hacen, convierten al átomo o molécula atacada en un radical libre, lo que puede derivar en una reacción en cadena, con resultados desastrosos para la célula (muerte o inicio de la formación de un tumor). El más conocido es el radical libre de oxígeno, al que le falta un electrón en su órbita más externa y tiene entonces un alto poder oxidante. Al “robar” un electrón a algún átomo perteneciente a alguna célula lo “oxida”. También se ha probado que, buscando el electrón que le falta, daña al ADN. Figura 1. Átomo de oxígeno “completo”, con 2 electrones en la órbita interna y 6 electrones en la órbita externa Figura 2. Un radical libre “robando” un electrón y, por lo tanto, generando otro radical libre 3 Todos los días en nuestro cuerpo billones de células mueren y son substituidas por nuevas células, las que son “fabricadas” por el cuerpo de acuerdo al “programa” establecido en el ADN. Si el ADN está dañado, la nueva célula es diferente de la antigua. Esta es la causa del envejecimiento del cuerpo humano. También la copia “mala” de la célula puede inducir una enfermedad degenerativa u otras enfermedades. El cuerpo produce antioxidantes (llamados enzimas), que son una fuerte defensa contra estos radicales libres altamente agresivos. Estos enzimas se vuelven mucho más eficientes si son “activados” por minerales, tales como selenio, magnesio y calcio. Un enzima le entrega o comparte uno o más electrones con el radical libre sin transformarse él mismo en un radical libre, es decir, los enzimas son moléculas electrónicamente altamente estables.

Si para una persona o animal la producción de radicales libres sobrepasa a la producción de antioxidantes, se pierde el equilibrio y comienza el daño de los radicales libres sobre las células del cuerpo. El equilibrio se puede perder por varias razones: polución ambiental (humo de cigarro, polvo, etc.), luz ultravioleta, contaminantes en las comidas (por ejemplo arsénico, cadmio, cuarzo, micotoxinas, etc.), exceso de comida, etc., que son agentes catalizadores de las reacciones químicas productoras de radicales libres. Una célula normal (por ejemplo de nuestra sangre) tiene un pH interno de alrededor de 7.4 (en realidad se considera un pH normal de una célula sanguínea a un valor en el rango 7.35 a 7.45). Una célula cancerígena es más ácida: tiene un pH de alrededor de 7 o todavía menor. Un cambio de 0.1 en el pH de una célula es muy perjudicial para su funcionamiento. Un cambio superior suele ser mortal para una célula. Está bien establecido que estos minerales, las zeolitas naturales correctamente activadas mediante procesos solamente mecánicos, pueden controlar los radicales libres y reducir las enfermedades, removiéndolos del cuerpo. Una zeolita natural micronizada forma enlaces covalentes con los radicales libres, barriéndolos literalmente. Una partícula de zeolita natural micronizada posee un número elevadísimo de electrones para compartir, por lo que su poder antioxidante es sumamente alto. Las zeolitas son eliminadas posteriormente a través de la orina y de las heces fecales. ¿Qué son las zeolitas naturales? Científicamente hablando, las zeolitas son minerales naturales de génesis volcánica. Cuando los volcanes despidieron sus cenizas sobre lagos nacientes, hace millones de años, las reacciones químicas resultantes entre las cenizas y el agua alcalina alteraron las cenizas en varias formas cristalinas de zeolitas. Estas zeolitas tienen una estructura única en la naturaleza y están clasificadas como aluminosilicatos hidratados. Esto significa que los cristales están formados principalmente por hidrógeno, oxígeno, silicio y aluminio. La principal característica de las zeolitas es que son sólidos cristalinos tridimensionales y microporosos. La estructura microporosa está exactamente definida, ya que el tamaño de los poros es prácticamente uniforme y es una característica fundamental de cada especie de zeolita natural. 4 Figura 3. Representación de una molécula de una variedad de zeolita, mostrando un microporo descompensado eléctricamente Las zeolitas naturales fueron descubiertas el año 1756 por el geólogo sueco Axel Fredick Cronstedt, quién las bautizó como zeolitas, ya que observó que perdían agua al ser calentadas. “Zeo” y “Lite” son palabras griegas que significan “piedra que hierve”. Las zeolitas naturales de aplicación en medicina son la clinoptilolita, la heulandita y la mordenita. Las zeolitas naturales micronizadas tienen una gran capacidad de absorber moléculas polares. De gran importancia en la captura de toxinas, las que en general son moléculas polares (micotoxinas, alcoholes, neurotoxinas, etc.). Figura 4. Clinoptilolita - Heulandita 5 Figura 5. Mordenita Otra característica importante que les da la estructura cristalina microporosa a las zeolitas es la habilidad para intercambiar cationes. Este proceso significa el intercambio de un

catión por otro. Un catión sale de la estructura microporosa y otro lo substituye. De gran importancia en la capacidad anticancerígena de las zeolitas, ya que esta propiedad implica la posibilidad de subir el pH a una célula cancerígena, haciendo que ésta muera. El mineral que contiene el yacimiento chileno de zeolitas naturales está formado por las tres especies de composición química mostrada a continuación: Clinoptilolita: (Na,K,Ca)2-3 Al3 (Al,Si) 2Si13O36 12H2O Heulandita: (Na,Ca)2-3 Al3 (Al,Si) 2Si13O36 12H2O Mordenita: (Na,K2,Ca2)2-3 Al2 Si10O24 7H2O Propiedades físico-químicas de las zeolitas Estabilidad pH: entre 0.5 y 13 Estabilidad térmica: 650 ° mínima Densidad aparente: 900 a 1300 (kg/m3) Densidad real: 1200 a 1500 (kg/m3) Capacidad de Intercambio Catiónico: 160 a 220 (meq/100gr) (alto CIC) Color: Blanco a blanco crema Diámetro de los microporos: 4 a 5.5 A° Solubilidad en agua: 0 Olor: Inodora Granulometría: 100% < 20 micrones 6 Casos de cura de diversas enfermedades a través de la ingestión de zeolitas naturales (Croacia, Estados Unidos, Chile) Las zeolitas naturales micronizadas pueden ayudar cuando los procesos biológicos del cuerpo están funcionando mal, causando enfermedades tales como: 1. Enfermedades de la piel Las zeolitas naturales micronizadas pueden acelerar la curación de heridas así como ayudar en el tratamiento de enfermedades infecciosas de la piel (herpes), dermatitis inflamatoria (psoriasis) y alergias y enfermedades de la piel (dermatitis, etc.). Además de estar tomando una dosis oral, se recomienda la aplicación externa de polvo sobre la parte abierta de la herida o enfermedad de la piel, unas pocas veces por día. 2. Enfermedades malignas Durante y después de la quimioterapia las zeolitas naturales micronizadas pueden ayudar a: Reducir las necesidades de analgésicos y narcóticos, Reducir/remover líquido de la cavidad abdominal (hidropesía del peritoneo), Mejorar los niveles de sedimentación, Aumentar los niveles de hierro, Aumentar el número de células sanguíneas, Mejorar la salud general del paciente para facilitar el tratamiento de la quimioterapia Paliar efectos secundarios tales como vómitos, náuseas estomacales, pérdida del apetito, pérdida de peso, caída de cabello, etc., Eliminar los hongos que aparecen a menudo durante la quimioterapia en la boca y esófago y hace la recuperación más difícil

3. Algunas enfermedades de los tejidos conectivos Las zeolitas naturales micronizadas pueden ayudar a que las articulaciones no produzcan dolores durante diferentes enfermedades relacionadas al colágeno (artritis reumatoide, lupus eritematoso) y fibrosis. 4. Enfermedades de giro (la parte lumbar) Las zeolitas naturales micronizadas pueden asistir significativamente en la reducción del dolor durante el lumbago y la ciática. 5. Enfermedades gastrointestinales 7 Pueden prevenir contracciones espasmódicas (colitis ulcerosa) y dolores. También ayuda regulando el movimiento intestinal Pueden contribuir a normalizar la super secreción estomacal Ayudan a regular la acidez estomacal 6. Diabetes Pueden ayudar a regular los niveles de azúcar en la sangre Mejorando la microcirculación, puede disminuir las complicaciones de la diabetes 7. Enfermedades cardiovasculares Pueden contribuir en la normalización de los latidos rítmicos del corazón (extrasístole de desconocida etiología, taquicardia), Pueden también asistir en la regulación de la presión sanguínea 8. Enfermedades de la sangre Pueden ayudar a la normalización de valores desordenados en enfermedades tales como anemia y glóbulos blancos. 9. Enfermedades del sistema nervioso y desórdenes neuromusculares Pueden ayudar a tranquilizar convulsiones, en la regulación de la tensión de los músculos, en eliminar espasmos musculares y reflejos patológicos, así como también asistir en la disminución de la frecuencia e intensidad de los ataques epilépticos. 10. Enfermedades del hígado Contribuyen a la mejoría de la condición general y ayuda a alcanzar valores normales de los enzimas hepáticos (AST, ALT, yGT). Testimonios de casos de enfermedades graves curadas con terapias que incluyen zeolitas naturales micronizadas Caso #1 - Complicación de diabetes Paciente B.B. Fecha de nacimiento: 1942. Diagnóstico: La diabetes fue diagnosticada en 1982. Hasta ese año, el paciente no tenía problemas médicos. 8 El tratamiento médico se basó en dieta alimenticia y aplicación de drogas hipoglicémicas. En 1995 su pierna derecha inferior fue amputada. Desde Mayo de 1996 ha estado aplicándose insulina. Desde marzo de 1999 han aparecido úlceras de varios tamaños en su pierna izquierda inferior. Sus heridas fueron tratadas con rivanol y povidona. No había dudas que en un futuro muy cercano su pierna izquierda inferior también debería ser amputada.

Este paciente ha estado tomando zeolitas naturales micronizadas (junto con insulina) desde Septiembre 22 de 1999, oralmente y poniendo polvo sobre las heridas. En Septiembre 22 eran visibles tres úlceras sobre la superficie de su pierna izquierda inferior (de 5, 3 y 1 cm). Se presentaban dolores fuertes en la parte inferior de la pierna con picazón intensa y malos olores alrededor de las úlceras. Efectos de las zeolitas naturales micronizadas (junto con la terapia médica prescrita): Después de 7 días – menos dolores y menos picazón, mejor dormir Después de 10 días – menor mal olor, aparición de tejido sano, así como el comienzo de la granulación Después de 30 días – las dos úlceras más pequeñas se cerraron completamente mientras que para la úlcera más grande la epitelización comenzó sobre los bordes Después de 75 días – completa epitelización de las dos úlceras más pequeñas y 90% de epitelización de la úlcera más grande. No hubo más signos de inflamación Después de 200 días – la úlcera más grande se cerró completamente Es importante mencionar que en el periodo de monitoreo los efectos de las zeolitas naturales micronizadas regularon la glicemia también. No hubo más dolores ni picazón. Caso #2 – Neurodermitis Paciente: I.P. Diagnóstico: Neurodermitis Año de nacimiento: 1969. Historial médico - Una menor de edad que sufría de bronquitis con espasmos. Después del segundo embarazo (1995) aparecieron cambios sobre la piel. Éstos eran más visibles sobre las manos, sobre ambos lados de los puños. El tratamiento médico se basaba en terapia con antialérgicos y corticoides. Después de aplicada la terapia, los cambios en la piel continuaron, con coloración roja, picazón y ardor. Un periodo más largo de terapia con corticoides provocó super infecciones bacterianas. Se presentó también un edema en las muñecas. 9 La paciente ha estado tomando zeolitas naturales micronizadas oralmente y en polvo desde Julio de 1999. 15 días después de haber estado tomando zeolitas naturales micronizadas el cuadro clínico era mejor, como también se presentaba menor coloración roja y picazón. Ya no habían edemas en las muñecas ni picazón ni ardor. La paciente está ahora en posición de hacer sus labores de casa sin guantes, lo que no era posible antes. Caso # 3 – Artritis Reumatoide Paciente A.P. Año de nacimiento: 1948.

Diagnóstico: Artritis reumatoide Año del diagnóstico: 1992 El tratamiento médico estaba basado en terapia física y medicamentos (analgésicos -Auropan, Ibuprofen). Status del paciente en Abril de 1999: El paciente tenía una inflamación seria con edemas en ambas muñecas, con articulaciones metacarpianas hinchadas, el codo derecho estaba flexionado, tenía limitado el movimiento en ambas rodillas y edemas en los tobillos de ambas piernas, así como limitada movilidad. Comenzó a tomar zeolitas naturales micronizadas en Abril de 1999. 7 días después de comenzar el tratamiento se notó una mejor movilidad de las articulaciones pequeñas. También disminuyó la necesidad de tomar analgésicos. 14 días más tarde mejoró la movilidad de las articulaciones mayores, junto con una disminución significativa de los edemas. Es importante mencionar que la ausencia por siete días de zeolitas naturales micronizadas deterioró los síntomas temporalmente. Desde ahí el paciente toma zeolitas naturales micronizadas regularmente y no ha tenido problemas con la movilidad y los edemas. Caso # 4 – Enfermedad o Mal de Crohn Paciente: M.P. Año de nacimiento: 1967. Diagnóstico: Enfermedad o Mal de Chron Fecha del Diagnóstico: Diciembre de 1998. Terapia: Sulfosalazin 3x1 Peptoran 2x1 Medrol 2x1 Comienzo de ingestión de zeolitas naturales micronizadas: Enero de 1999. Durante diez meses el paciente pasó periodos sin tomar zeolitas naturales micronizadas regularmente. La dosis también era diferente. Él tomaba la terapia médica prescrita 10 regularmente pero disminuyó las dosis de sulfosalizin y peptoran y eliminó completamente medrol (hormona esteroide). El paciente aumentó su peso corporal en 20%. El paciente observó disminución de los dolores y el número y consistencia de los movimientos intestinales se hizo normal. Caso # 5 - Cirrosis biliar Paciente: K.K. Año de nacimiento: 1934. Diagnóstico: Cirrosis biliar Historial médico: - La cirrosis biliar fue diagnosticada en 1995 (clinicamente, laboratorio, ultrasonido y patohistología). Se presentaba un cuadro de debilidad, pérdida de vitalidad, flojera y somnolencia. De tiempo en tiempo aparecían dolores bajo la costilla derecha y desplazándose hacia atrás. También se presentaba un edema sobre los tobillos. Terapia: Ursofalk 800 g diariamente Ingestión de zeolitas naturales micronizadas – Diciembre de 1998 15 días después de estar tomando zeolitas naturales micronizadas, el paciente se sintió «más fuerte y vigoroso» 45 días después de estar tomando zeolitas naturales micronizadas el edema alrededor de los tobillos desapareció, mientras los dolores bajo la costilla derecha fueron menos significativos. Resultados de ultrasonido:

Junio de 1999. - el hígado había aumentado levemente El paciente se sintió muy bien y era capaz de llevar a cabo actividades normales sin sensación de cansancio. Diciembre de 1999. – El hígado tenía tamaño normal Caso # 6 – Enfermedades malignas Entre cerca de 50 pacientes con procesos malignos (la mayoría del sistema mamario, respiratorio y gastrointestinal), se observó la influencia de zeolitas naturales micronizadas. Para la mayoría de los pacientes se aplicaba tratamiento de quimioterapia e irradiación. SI NO Disminución de dolores 31 4 Mejoría del apetito 37 10 Mejoría de la condición general 40 7 Mejoría de la salud general 47 0 11 Mejoría de la condición física 36 11 Otros casos en Croacia (testimonios directos de los pacientes) Caso 1. Paciente: S.B. Diagnóstico: Cáncer al pulmón Testimonio: Estaba por sufrir otro tratamiento de quimioterapia cuando escuché acerca de las zeolitas naturales micronizadas. Decidí intentar la terapia con las zeolitas naturales micronizadas. El resultado es sorprendente: el tumor y la metástasis se fueron. No siento dolores, mi cabello creció nuevamente. Globalmente puedo decir que me siento “en la cima”. Caso 2. Paciente: I.S. Diagnóstico: Tumor maligno en la vejiga Testimonio: En lugar de aceptar una remoción quirúrgica de mi vejiga, le di una chance a las zeolitas naturales micronizadas. El efecto sorprendente después de tres meses: no se encontraron células cancerosas ni metástasis. Una sustancia aún no examinada en forma completa, un mineral, una vitamina, o como quiera llamarse, me ha ayudado. De acuerdo al último diagnóstico, no tengo cáncer. Caso 3. Paciente: I.S. Diagnóstico: Hemorragia gástrica y dolores de estómago Testimonio: las zeolitas naturales micronizadas pararon mis fuertes dolores de estómago y hemorragias gástricas. Hoy día, me siento sano, con vitalidad y con buen estado físico y volví a trabajar 16 horas diarias.. 12 Caso 4. Paciente: N.M. Diagnóstico: Hipercolesterol

Testimonio: Después de seis semanas de aplicación de las zeolitas naturales micronizadas, mi nivel extremadamente alto de colesterol volvió a la normalidad. También se redujo los sedimentos sobre los ojos. Caso 5. Paciente: L.Z. Diagnóstico: Diabetes, pancreatitis, piedras en la vesícula Testimonio: Por años he sufrido de una pesada diabetes y algunas otras molestias. Pero después de un tratamiento intensivo con las zeolitas naturales micronizadas, ahora estoy libre de dolores y no necesito usar más insulina. He vuelto atrás a mi vida anterior – Puedo trabajar nuevamente y mi calidad de vida ha mejorando enormemente. Caso 6. Paciente: D.S. Diagnóstico: Cáncer inoperable al intestino, metástasis en el hígado y el páncreas Testimonio: Fue muy duro escuchar este diagnóstico y no sabía que hacer. Fue una suerte escuchar acerca de las zeolitas naturales micronizadas. Después de 6 meses de aplicar la terapia de las zeolitas naturales micronizadas la metástasis desapareció y he tenido una buena condición. Día a día me siento mejor. He vuelto a mi vida familiar normal – y a mi vida de trabajo. Caso 7. Paciente: T.M. Diagnóstico: Cáncer intestinal Testimonio: Desde 1994 he tenido varias operaciones en clínicas de Munich y Zurich. A pesar de la quimioterapia y la radiación mi condición empeoró. En mayo de 1998 partí con un tratamiento con concentrado de papaya y las zeolitas naturales micronizadas (dos cápsulas de 500 mg cada media hora). Ya en noviembre de 1998 los resultados dieron lugar a la esperanza – ni metástasis, ni vómitos, ni presión en el estómago, me sentaba normalmente y, lo más importante, casi sin dolores. Mi bienestar se hizo cada vez mejor y mejor y hoy día me siento O.K. Caso 8. Paciente: N.M. Diagnóstico: Esclerosis múltiple 13 Testimonio: Después de 3 ataques, un tratamiento intensivo (24 cápsulas de de 500 mg por día) con las zeolitas naturales micronizadas me condujo a un resultado sorprendente: ya después de 7 días sentí que las cosas iban mejorando, después de 6 semanas todos los síntomas desaparecieron. Ni más parálisis, ni perturbaciones visuales – el baile de las letras desapareció. De nuevo adquirí potencia y energía. Caso 9. Paciente: M.L. Diagnóstico: Hepatitis B Testimonio: Vivo en Berlín por más de 25 años y he montado una empresa exitosa, pero tenía una baja calidad de vida, debido a la Hepatitis B. Esto cambió después de un

tratamiento intensivo de 12 días con zeolitas naturales micronizadas. Ahora no tengo más hepatitis B, mi calidad de vida es extremadamente mejor y me siento nuevamente un hombre feliz. Además, mi riñón contraído creció nuevamente desde 4.5 cm a su tamaño normal de 11.5 cm y funciona normalmente. Caso 10. Paciente: K.P. Diagnóstico: Migraña, calambres en la pierna izquierda Testimonio: Por más de 20 años he sufrido de migraña y mis calambres se hicieron tan intensos que me despertaban durante el sueño. Desde que comencé a tomar zeolitas naturales micronizadas no tengo más dolores de cabeza, los calambres desaparecieron, no tengo más problemas durante el sueño, sino más vitalidad y bien estar. 14 Productos en el mercado mundial basados en zeolitas naturales para aplicación en seres humanos Uno de estos productos es el Megamin (www.megamin.net y www.megaminworldwide. com/Zeolite-Mineral.html), suplemento alimenticio, que fue desarrollado en Croacia y es fabricado en Italia, Alemania y Austria, está identificado como un producto fuertemente antioxidante. Actualmente se vende a través de Internet, en las páginas indicadas. Un segundo producto, de origen cubano, es el Enterex (Armbruster T., “Clinoptiloliteheulandite: applications and basic research”. Studies in Surface Science and Catalysis 135. In “Zeolites and Mesoporous Materials at the Dawn of the 21th Century”. Galarnau, Renzo, Faujula and Vedrine (Editors), Elsevier Science B.V., 13-27 (2001)) que, como su nombre lo indica, fue ideado para usarse en el control de la colitis, aprovechando las características de absorción de agua y de toxinas de las zeolitas naturales. Un tercer producto, de origen norteamericano, es el Sir Activ, un producto de tipo spray, diseñado para revitalizar la piel, gracias al poder de control de los radicales libres que se generan en las células epiteliales, característica que poseen las zeolitas naturales micronizadas. Posteriormente, esta misma empresa modificó este producto hacia una nueva generación, más completa, llevando al mercado el producto X-Trap Daily Gentle Face Wash, más reciente, que es un producto para limpieza de la piel (http://www.mygayweb.com/shopping/product.asp?P_ID=121). Otro producto, desarrollado por la empresa “Natural Healing House”, puesto en el mercado internacional, parecido al Megamin, se ha llamado sugestivamente Liquid zeolite (http://zeolitehelp.com/zeolitesupplement), y fue inicialmente puesto en el mercado como polvo encapsulado y con el nombre Zeo pH Plus, está indicado como un restablecedor del pH celular. Este producto viene a ser una confirmación en el mercado internacional del fuerte poder antioxidante que tiene las zeolitas naturales micronizadas, en el combate en forma natural de las enfermedades degenerativas y que tiene otros efectos altamente benéficos para los seres humanos. En la actualidad, el producto se denomina Natural

Cellular Defense y es comercializado por la empresa canadiense Waiora (http://santeenergetique. over-blog.com/categorie-10000651.html) Otro producto que ha salido más recientemente al mercado, de la empresa australiana (http://www.bionatural.com.au/index.php? action=productcatalogue&prodcat_id=347&prod_id=3991&pageID=3928§i onID =3928) BioNatural Follow Nature, es el NanoPrime, que está indicado como antioxidante, desintoxicante y que contiene además de las zeolitas naturales micronizadas (principalmente clinoptilolita), algunos nutrientes minerales, como carbonato de calcio y de magnesio. También recientemente, la empresa norteamericana Miakota, bajo el moderno concepto de “nutrición celular” (http://www.miakota.com/products/moondrops.htm), lanzó al mercado un superproducto, que llamó MoonDrops Z+, un producto que restablece el balance del cuerpo, la juventud y vitalidad, ya que contiene la llamada Zeolita Quantum Super-Segura (clinoptilolita micronizada), suspendida en ácido húmico concentrado, lo que 15 aseguraría que el 100% de las zeolitas tendrían como destino las células. Los resultados de laboratorio y en seres humanos han demostrado que este producto remineraliza las células, regenera el ADN, balancea el pH del cuerpo, captura metales pesados y toxinas altamente perjudiciales y los elimina del cuerpo y balancea el sistema digestivo. Así, la empresa productora señala que este producto es el suplemento antienvejecimiento más importante que jamás haya aparecido en el mercado. Por último, la empresa norteamericana Oasis Advanced Wellness (http://www.oasisadvancedwellness.com/products/zeomax.html) ha lanzado recientemente al mercado el suplemento alimenticio ZeoMax FA, el que contiene zeolitas naturales micronizadas suspendidas en ácido fúlvico orgánico. Este producto está caracterizado como un “suplemento alimenticio premium para proteger la salud celular”. Según información entregada por esta empresa, el ácido fúlvico sería la forma más eficiente de entregar minerales a las células humanas y el producto ZeoMax sería un gran antioxidante, con inigualables propiedades antienvejecimiento y de desintoxicación celular. 16 Clasificación de la IARC y FDA de las zeolitas naturales Un hecho altamente positivo es que un producto basado en zeolitas naturales es un producto 100% natural, 100% no tóxico y 100% no contaminante. Como algunos minerales son cancerígenos (cuarzo, arsénico, etc.), un paso importante en la posible utilización de las zeolitas naturales en medicina humana fue investigar una posible relación con el cáncer. La investigación la dirigió la institución internacional IARC (International Agency for

Research on Cancer), la que después de estudiar todos los antecedentes reunidos clasificó a las zeolitas naturales (variedades de interés para Chile: clinoptilolita, heulandita y mordenita) en el Grupo 3: “no clasificables como cancerígenas”. Este hecho abrió definitivamente la puerta para usar con seguridad zeolitas naturales en alimentación y medicina humana. También es interesante destacar que la clinoptilolita está aprobada por la FDA como suplemento alimenticio. Por último, una investigación exhaustiva en Croacia ha demostrado que las zeolitas naturales micronizadas son totalmente no tóxicas. En efecto, la investigación mostró que las zeolitas naturales no tienen toxicidad aguda, subcrónica o crónica de ninguna especie. En la última década a aumentado la investigación científica sobre acción de las zeolitas naturales como grandes antioxidantes, así como el entendimiento de los mecanismos mediante los cuales las zeolitas tienen habilidad anticancerígena así como antimetástasis (ver algunas referencias al final de este folleto). Finalmente, se puede mencionar que últimamente se ha verificado la acción antiviral que tiene la clinoptilolita, pero la investigación acerca de este hecho está en sus primeras etapas (ver referencia 9). Otros usos de las zeolitas en Alimentación y Medicina Se sabe también que en Rusia se fabrican chocolates y galletas que contienen zeolitas naturales en su formulación. En Croacia, Rusia, Cuba, Inglaterra, Japón y España se está investigando exhaustivamente usos de las zeolitas naturales en Medicina: tratamiento de heridas, liberación controlada de feromonas, tabletas vaginales, etc.. Dosis y frecuencia de aplicación de zeolitas naturales para ingestión en forma preventiva y en forma curativa En resumen, cuando las zeolitas naturales micronizadas son ingeridas por un ser humano (y también en el caso de los animales, por cierto), tienen tres efectos bien definidos, los que pueden resumirse en: 1. Efecto antioxidante: los radicales libres son fijados a la estructura de las zeolitas mediante enlaces covalentes. Una partícula micronizada de una zeolita natural posee innumerables electrones para compartir y controlar los radicales libres, 2. Efecto antitoxicidad: las toxinas, por tratarse de moléculas polares, son absorbidas y adsorbidas por las zeolitas tanto en sus microporos como en la superficie de las partículas micronizadas, dejando inactivo el mecanismo de acción de las toxinas, mecanismo muchas veces cancerígeno, 3. Efecto anticancerígeno: las células cancerígenas son más ácidas que las células normales. Las células cancerígenas viven a un pH de alrededor de 7. Las células normales viven a un pH de alrededor de 7.4. Las zeolitas naturales cuando entran en contacto con una célula cancerígena le modifican su pH, subiéndolo a alrededor de 7.4, debido a un fenómeno de intercambio catiónico, por lo que la célula cancerígena finalmente muere. La experiencia croata con miles de enfermos ha conducido a las siguientes dosis de consumo de zeolitas naturales, para efecto curativo de una variedad de enfermedades, tanto

malignas como no malignas. Las dosis diarias que deben ingerirse de zeolitas naturales micronizadas varían entre 1.5 y 12 gramos Las enfermedades degenerativas con alto grado de avance, tales como cáncer de diferente índole, con metástasis, se deben tratar con una dosis diaria de 12 gramos (por ejemplo, cáncer al hígado, cáncer al pulmón, cáncer intestinal, cáncer pancreático, etc.). Es altamente recomendable dividir la dosis diaria en dosis más pequeñas lo más cercanas posible entre ellas (se han reportado casos de curas muy rápidas cuando se ingiere zeolitas micronizadas cada media hora, excepto en el horario nocturno de descanso) Se ha determinado también que cuando se ingiere una dosis mínima de 4 gramos diarios de zeolitas naturales, los pacientes (tanto sanos como enfermos) consiguen aumentar ostensiblemente su status antioxidante (TAS, en inglés, “Total Antioxidant Status”) Las enfermedades no malignas, tales como Parkinson, esclerosis múltiple, lupus eritematoso, diabetes, hepatitis A, B y C, artritis reumatoide, psoriasis, etc., 18 deben tratarse con una dosis que varía entre 1.5 y 9 gramos diarios, dependiendo de lo avanzada que esté la enfermedad. Por cierto, en todos los casos es conveniente repartir la dosis diaria en dosis a ingerir en horarios lo más próximos posible entre ellos (cada media hora en casos más graves). De todas formas, si no se sigue un método de ingestión muy seguida debido a que la enfermedad no está muy avanzada o no es muy grave, se recomienda tres dosis diarias: una dosis antes del desayuno (ideal media hora antes), media hora antes del almuerzo (si se olvida, una hora después del almuerzo) y una dosis media hora antes de la cena (o una hora después de la cena). Finalmente, podemos decir con plena seguridad que las zeolitas micronizadas pueden consumirse en forma preventiva, en cualquier dosis, aunque recomendamos una dosis de al menos 4 gramos diarios, lo que permitirá conservar un sistema inmunológico muy alto. Por cierto, este sistema inmunológico alto permite la prevención de las enfermedades generativas, entre ellas el temido cáncer. 19 Referencias 1. Pavelic K., Hadzija M., Bedrica J., Pavelic J., Dikic I., Katic M., Kralj M., Bosnar M.H., Kapitanovic S., Poljak-Blazi M., Krizamac B.S., Stojkovic R., Jurin M., Subotic B. and Colic M., “Mechanically treated natural clinoptilolite zeolite - new adjuvant in anticancer therapy”, J Mol Med 78, 708-720 (2001) 2. Pavelic K., Katic M., Sverko V., Marotti T., Bosnjak B., Balog T., Stojkovic R., Radacic M., Colic M. and Poljak-Blazi M., “Immunostimulatory effect of natural clinoptilolite as a possible mechanism of its antimetastatic ability”, J Cancer Clin Oncol 128, 37-44 (2002) 3. Kralj M. and Pavelic K., “Medicine on a small scale. How molecular medicine can benefit from self-assembled and nanostructured materials”, EMBO reports Vol 4, 1008-1012 (2003)

4. Colic M. and Pavelic K., “Molecular mechanisms of anticancer activity of natural dietetic products”, J Mol Med. 78(6), 333-336 (2000) 5. Pavelic K., Katic M., Zarkovic N., Sverko V., Marotti T., Kralj M., Zarkovic K., Bosnjak B., Balog T., Stojkovic R., Radacic M., Colic M. and Poljak-Blazi M., “Antioxidative and immunostimulatory effect of natural clinoptilolite in vivo”, Technical report from Rudjer Boskovic Institute and Medicine Faculty of the Univesity of Zagreb, Croatia (2001) 6. Zarkovic N, Zarkovic K, Kralj M, Borovic S, Sabolovic S, Blazi MP, Cipak A, Pavelic K., “Anticancer and antioxidative effects of micronized zeolite clinoptilolite”, Anticancer Res. Mar-Apr 23(2B), 1589-95 (2003) 7. Muck-Seler D, Pivac N., “The effect of natural clinoptilolite on the serotonergic receptors in the brain of mice with mammary carcinoma”, Life Sci.;73(16), 2059-2069, Sep 5 (2003) 8. Martin-Kleiner I, Flegar-Mestric Z, Zadro R, Breljak D, Stanovic Janda S, Stojkovic R, Marusic M, Radacic M, Boranic M., “The effect of the zeolite clinoptilolite on serum chemistry and hematopoiesis in mice”, Food Chem Toxicol., 39(7), 717-727, Jul (2001) 9. Grce M. and Pavelic K., “Antiviral properties of clinoptilolite”, Journal of Microporous and Mesoporous Materials, 79(1-3), 165-169, July (2005) Nota: estas referencias técnicas y otras pueden ser solicitadas directamente al Dr. Arturo Barrientos ([email protected]) Preparado por: Dr. Arturo Barrientos R. Universidad de Colombia Arymo Ltda. Concepción, Marzo de 2007 E-mail: [email protected]

Zeolite Benefits Zeolite is a Natural Detox - With No Side Effects!

What is a Zeolite Zeolites are natural volcanic minerals that are mined in certain parts of the world. When volcanoes erupt, molten lava and thick ash pour out. Because many volcanoes are located on an island or near an ocean, this lava and ash often flows into the sea. Thanks to a chemical reaction between the ash from the volcano and the salt from the sea, amazing minerals like zeolites are formed in the hardened lava over the course of thousands of years. What makes zeolites so amazing is the fact that it’s not only one of the few negatively-charged minerals found in nature, but it also has a very unique structure. Zeolites have large, vacant spaces––or cages––that allow space for large, positively charged ions to be attracted to it, then trapped and eliminated from the body. What Makes Zeolite So Valuable?

The silicon building block in Zeolite is electrically neutral, but the aluminum building block carries a negative charge, which creates charged sites throughout the entire crystal structure. A three-dimensional framework produces net negative charge that traps environmental pollutants and is balanced by the exchangeable cations Calcium, Magnesuim, Phosphate. The clinoptilolite attracts positive minerals such as calcium, magnesium, potassium, sodium and iron. These common positive cations then are displaced by heavy metals such as cadmium, mercury, nickel, and arsenic and removed safely from the body. Smaller Ions such as Mercury and Cadmium are pulled deeply into the cage of the zeolite and held securely for safe elimination. •Allows for selective chelation: Hg > Pb > Sn > Cd > As > Al > Sb > Fe > Ni verified by Atomic Absorption Spectroscopy •Clinical Studies in “normal” volunteers: 5-7 fold increase urinary excretion within 1 week •Clinical Studies in coal miners: 12-15 fold increases in urinary excretion & decreases in hair levels of toxic metals

Top 5 Zeolite Benefits: 1. 100% safe and non-toxic at any level: All traces of the mineral are completely eliminated out of the body within 6 to 8 hours. It's safe for children, pets, pregnant women and nursing mothers. It is also safe to take with most medications (as long as they are not heavy metal based), but as always you should check with a medical professional first. * 2. Removes heavy metals & toxins: Micronized zeolite has the perfect molecular structure for capturing and removing heavy metals from the body without removing healthy ions and minerals. (as explained in diagram above). Many people report feeling increased energy, clarity and vitality after removing heavy metal build-up. * 3. Helps balance body's pH levels to a healthy alkalinity: Whenever micronized zeolite is introduced to the body, it buffers the system towards slightly alkaline (pH 7.35 to 7.45), which is a optimum pH for the human body. Zeolite attracts and then buffers excess protons which cause acidity and in this way can help many conditions from acid reflux to Candida and arthritis. 4. May help reduce cancer risk: There is clear evidence that micronized zeolite not only removes toxins that can cause cancer (75% or more of cancers may be toxin-related). This does not mean that zeolite is a cancer treatment, it is a useful supplement to integrate into a treatment program.* 5. Zeolite is very easy to take: Most detoxification products are difficult to take and many must be injected into the blood or administered such as an enema. Zeolite works at the cellular level, has no taste or odor and it can be taken on an empty stomach. (you wont even know you are taking it) Questions about Zeolite...

How long will it be before I see results? This is difficult question to answer and all depends on the individual person. Everyone shows toxicity in their body in different ways. Some may have bad skin, some may show severe medical issues. Based on the persons exposure to toxins and heavy metals, there are different levels in people. People also respond differently to treatment. Our general recommendation is to take the product for 90 days and then be reevaluated by your medical professional to see what progress has been made. Please make sure that you are also taking the recommended dosage based on your needs to ensure that you are receiving the optimum benefit from the product. * I have had problems with side effects of other detoxifying products, will I have the same problem with your products? Toxicity in the body can show itself in different ways in different people. Most detoxifying products have side effects but our Zeolite products generally do not have any side effects. Other detoxifying products pull heavy metals and toxins out of the tissue and flood the bloodstream with these toxins. You body is then overwhelmed by being hit with all of these toxins at once, which is what cause all the unpleasant side effects.

With Zeolite, when the toxins and heavy metals are pulled out of the tissue, they are trapped in the zeolite cage and you body is not re-exposed to them, thereby reducing the possiblility of any negative side effects. Although possible reactions may differ by individual. Why don't you manufacture a liquid Zeolite? The simple answer is because there is no such thing. It is a marketing ploy made up by a MultiLevel Marketing company who manipulated information about a patent from an inventor who never claimed it was Zeolite any longer after creating it. He destroyed the beneficial cage structure and negative charge by liquefying it with hydrochloric acid. He was trying to create an injectable drug and never even claimed it was ingestible. All published scientific studies ever done on Zeolite showing it beneficial, were done on the powdered mineral. There was one study quoted on the internet by the MLM company's distributors and we later proved that it was a lie made up to sell product by them.. The company that they claimed did the study, was actually the person that they originally licensed the patent from who later told the truth that the study never existed after the MLM company stopped paying the licensing fees to them.

TOP 5 DE LOS BENEFICIOS DE LA ZEOLITA

1 . 100 % seguro y no tóxico a cualquier nivel : Todos los rastros del mineral se eliminan por completo fuera del cuerpo dentro de las 6 a 8 horas . Es seguro para los niños , animales domésticos , las mujeres embarazadas y las madres lactantes . También es seguro tomar con la mayoría de los medicamentos (siempre y cuando no sean de metales pesados en base ) , pero como siempre debe consultar con un profesional médico primero . * 2 . Elimina los metales pesados y toxinas : zeolita micronizada tiene la estructura molecular perfecta para capturar y eliminar los metales pesados del cuerpo sin la eliminación de los iones y minerales saludables . ( como se explica en el diagrama de arriba ) . Muchas personas dicen sentir mayor energía , claridad y vitalidad después de la eliminación de metales pesados acumulación . * 3 . Ayuda a los niveles de pH del cuerpo a un equilibrio saludable alcalinidad : Siempre zeolita micronizada se introduce en el cuerpo , que amortigua el sistema hacia ligeramente alcalino ( pH 7,35 a 7,45 ) , que es un pH óptimo para el cuerpo humano . La zeolita atrae y luego amortigua protones que causan el exceso de acidez y de esta forma puede ayudar a muchas condiciones de reflujo ácido a Candida y la artritis .

4 . Puede ayudar a reducir el riesgo de cáncer: Hay pruebas claras de que la zeolita micronizada no sólo elimina las toxinas que pueden causar cáncer ( 75 % o más de los cánceres pueden ser relacionados con la toxina ) . Esto no significa que la zeolita es un tratamiento contra el cáncer , que es un complemento útil para integrar en un programa de tratamiento . * 5 . La zeolita es muy fácil de tomar : La mayoría de los productos de la desintoxicación son difíciles de tomar , y muchos deben ser inyectados en la sangre , o se administran como un enema. Zeolita funciona a nivel celular , no tiene sabor ni olor y puede ser tomado con el estómago vacío . ( que incluso no sabe que está tomando ) Preguntas sobre Zeolita ... ¿Cuánto tiempo pasará antes de ver resultados? Esta es una pregunta difícil de responder , y todo depende de la persona individual. Todo el mundo muestra toxicidad en su cuerpo de diferentes maneras . Algunos pueden tener problemas de piel , algunos pueden mostrar problemas médicos graves. Sobre la base de la exposición de las personas a las toxinas y los metales pesados , hay diferentes niveles en las personas . Las personas también responden de manera diferente al tratamiento. Nuestra recomendación general es tomar el producto durante 90 días y luego ser reevaluado por su profesional médico para ver lo que se ha avanzado . Por favor, asegúrese de que usted también está tomando la dosis recomendada en base a sus necesidades para asegurarse de que está recibiendo el beneficio óptimo del producto. * He tenido problemas con los efectos secundarios de otros productos desintoxicantes , voy a tener el mismo problema con el producto? La toxicidad en el cuerpo puede manifestarse de diferentes maneras en diferentes personas. La mayoría de productos de desintoxicación tienen efectos secundarios, pero nuestros productos zeolita generalmente no tiene efectos secundarios . Otros productos desintoxicantes tiran los metales pesados y las toxinas de los tejidos y las inundaciones en el torrente sanguíneo con estas toxinas. Tu cuerpo se siente abrumado después por ser golpeado con todas estas toxinas a la vez , que es lo que causa los efectos secundarios desagradables. Con zeolita , cuando las toxinas y los metales pesados son sacados del tejido , se encuentran atrapados en la estructura de la zeolita y que el cuerpo no se re- expuestos a ellos , reduciendo de este modo la possiblility de efectos secundarios negativos . Aunque las reacciones posibles pueden diferir según la persona . ¿Por qué no fabricar una zeolita líquida ? La respuesta simple es que no hay tal cosa . Se trata de una estratagema de marketing realizada por una empresa de marketing multinivel que manipuló la información sobre una patente de un inventor que nunca afirmó que era zeolita por

más tiempo después de crearlo. Él destruyó la estructura de la jaula beneficiosa y carga negativa licuando con ácido clorhídrico. Él estaba tratando de crear un fármaco inyectable y nunca llegaron a afirmar que era ingerible . Todos los estudios científicos publicados realizados sobre zeolita mostrando que es beneficioso , se realizaron en el mineral en polvo. Hubo un estudio citado en el Internet a través de distribuidores de la compañía de MLM , y después nos demostró que era una mentira hecha para vender productos por ellos .. La empresa que según ellos hizo el estudio , era en realidad la persona que originalmente la licencia de la patente de la que más tarde le dijo a la verdad de que el estudio nunca existió después de la compañía de MLM dejó de pagar los derechos de licencia para ellos.

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ORIGINAL STUDY © 

Emmanouil Karampahtsis, Doctor of Naturopathic Medicine 14300 North Northsight Boulevard #207 Scottsdale, Arizona 85260 December 2012

Zeolite: Investigation of the Effectiveness and Safety as an Oral Chelating Agent for Heavy Metals. A comparison between different commercially available preparations

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ABSTRACT Background This case study was performed to evaluate the effectiveness of clinoptilolite zeolite (“zeolite” herein) as an oral chelating agent for heavy metals. Zeolite is a hydrated aluminosilicate with symmetrically stacked alumina and silica tetrahedra which result in an open and stable three dimensional honey comb structure with a negative charge. The negative charge within the pores is neutralized by positively charged ions (cations) such as calcium. Historically, zeolite has been used as a commercial absorbent, and more recently in the dietary supplement industry as a detoxifier. Methods Three different commercially available zeolite preparations for oral consumption were used: an oral spray, oral drops, and a powdered preparation. The chelating capabilities of the different zeolite preparations on 20 different heavy, and potentially toxic, metals were measured in urinary excretion in 20 human subjects. The excretion rates were compared to baseline (nonconsumption) measurements to ensure consistency. The safety was evaluated with pre and post testing of blood counts and chemistry, as well as liver and kidney function. Results It was possible to observe the capability of different zeolite preparations to increase the excretion of heavy metals from the human body in a safe manner. The effectiveness of three different zeolite preparations was observed. Conclusions When properly prepared as an oral supplement, zeolite can provide detoxification support to the human body to rid itself of heavy and toxic metals with minimal or no side effects. This can include applications to address lead, mercury or radiation poisoning.

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KEYWORDS Zeolite; oral chelation; heavy metal removal; clinoptilolite. ____________________________________________________________________________________

BACKGROUND There are several commercially available preparations of zeolite in capsule, drop, powdered, and spray forms. They all claim the capacity of zeolite to work as a chelating agent on different heavy metals. Zeolite has been rated Generally Regarded As Safe (GRAS) for human consumption by the Federal Drug Administration (FDA) and it has been used commercially for water filtration for years. Most studies published show the effectiveness of zeolite to clean up contaminated water from heavy metals and other toxins. The lack of human studies proving the effectiveness of zeolite as an oral chelating agent was the reason to perform this trial. The three zeolite preparations that were tested were the following: oral drops (Waiora, Natural Cellular Defense, Boca Raton, Florida, USA), powdered zeolite (ZEO Health, Zeolite Pure, Valley Cottage, New York, USA), and an oral spray (Results RNA, ACZ Nano Extra Strength, Salt Lake City, Utah, USA). The trial compared the higher doses recommended by each of the liquid (oral drops and oral spray) preparations’ respective companies, to the minimum dose recommended by the powdered zeolite preparation’s company. Our testing hypothesis is that zeolite, being an effective chelating agent of heavy metals in the body, should increase the excretion of those metals that it binds with, in urine. The anticipated outcome of our hypothesis is that the use of zeolite should increase the excretion of heavy metals in urine in comparison to non-use of zeolite. Provided that other parameters are fairly constant, such as the introduction of new heavy metals in the body (e.g. from consumption of contaminated seafood), we should be able to measure the difference of the heavy metal excretion in urine following consumption of zeolite. ____________________________________________________________________________________

METHODS The trial was organized in accordance with the Declaration of Helsinki, was registered with Current Controlled Trials Ltd (Registration Number ISRCTN12861674) and was performed from January through March 2012. To be eligible for the trial, participants needed to be above eighteen years of age, not pregnant or breastfeeding, and not currently taking heavy metal based medications. Participants were informed of the trial protocol, laboratory testing requirements, and their performance expectations prior to enrollment. Each participant needed to provide oral consent and meet the eligibility requirements in order to be enrolled in the trial. Recruitment started the week prior to

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onset of study, January 18th 2012. Twenty participants were randomly assigned to alternating groups (Group A or Group B) based on the order in which they arrived to obtain the testing materials. The trial took place and data collection was performed in one location, Lipogenex Anti-Aging Center in Scottsdale, Arizona, with the laboratory testing outsourced to Genova Diagnostics in Asheville, North Carolina. Analysis was performed according to Genova Diagnostics’ standard procedures. The laboratory (Genova Diagnostics) was blind as to if any and which chelating agent was present in the testing process, both at baseline and during zeolite intake. The primary measure to assess the effectiveness of each zeolite preparation was a urinalysis test to record the excretion levels of each participant for twenty different heavy metals. The secondary measure to assess the safety of the powdered zeolite preparation was a blood test to evaluate any changes in the blood count and chemistry, liver and/or kidney function. All participants were placed on an all-seafood restricted diet for a week prior to the trial and during the time of the trial, until they completed all urine measurements for heavy metals. This measure was taken as a control in order to prevent any new contamination that might alter the excretion rates between participants. All participants received a complete blood count and comprehensive metabolic panel as a baseline assessment prior to onset of the trial. This measure was taken to compare results after the consumption of zeolite to assess safety. Each participant received a six hour timed urine collection and analysis for heavy metals as a baseline to assess the levels of metals their body is able to excrete without the help of any chelating agent. For the primary outcome, Group A (10 participants) was tested only on the powdered zeolite preparation (Zeolite Pure by ZEO Health), and Group B (10 participants) was tested first on a liquid preparation, either oral drops (Natural Cellular Defense by Waiora) or oral spray (ACZ Nano Extra Strength by Results RNA), and then on the powdered zeolite preparation (Zeolite Pure by ZEO Health). Both groups were compared to each other when tested on the powdered preparation for the same amount of time, making Group A the control for this portion of the trial. Since all participants took some form of zeolite, the only true control was the individual measurements before and after consumption of any of the zeolite preparations. Group A consumed one scoop (5 grams) of the powdered zeolite preparation (Zeolite Pure by ZEO Health) for 5 days, totaling 5 grams of pure zeolite per day. One scoop was the lowest recommended dose from the supplement company (ZEO Health). On the morning of the 6th day participants consumed one scoop (5 grams) of the powdered zeolite preparation and collected all urine for 6 hours. First morning urine was discarded by all participants. All participants received 2 liters of bottled water and were asked to consume it within five hours during the urine collection time. A sample of the collected urine was sent for analysis for heavy metal excretion to Genova Diagnostics.

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Group B was assigned randomly either the zeolite oral spay (ACZ Nano Extra Strength by Results RNA) or the zeolite oral drops (Natural Cellular Defense by Waiora). Participants consumed the higher recommended dose by the supplement companies (Results RNA and Waiora, respectively) for 5 days. Five participants consumed 8 sprays three times per day of the oral spray preparation, totaling 28.32 milligrams (0.02832 grams) of zeolite per day. The other five participants consumed 10 drops three times per day of the oral drops preparation, totaling 240 milligrams (0.24 grams) per day. On the 6th day, they consumed the same higher recommended dose of their respective zeolite preparation and collected all urine for 6 hours (excluding first moring urine as above). Participants were given two liters of bottled water and asked to consume it within five hours during the urine collection time. A sample of the collected urine was sent to Genova Diagnostics for analysis for heavy metal excretion. After the collection of the urine, Group B received another blood test (complete blood count and comprehensive metabolic panel) to evaluate any impact of the consumed zeolite on the liver, kidney function, and blood chemistry (electrolytes). After the blood test was performed, participants were placed on a seven day break from all zeolite preparations to allow the body to return to the baseline state of excretion. All participants in Group B continued avoiding all seafood to prevent any potential contamination during the trial. Group B, after the seven day break from all zeolite preparations, consumed one scoop (5 grams) of the powdered zeolite preparation (Zeolite Pure by ZEO Health) for 5 days. This was done in order to compare effectiveness of the two different types of zeolite preparations (liquid and powdered) on the same participants, since the powdered zeolite preparation contained a much larger amount of zeolite per dose than either of the liquid preparations. We wanted to observe if the powdered zeolite preparation (Zeolite Pure by ZEO Health) had stronger chelating results on the same participants compared to the other two liquid preparations. On the 6th day, participants consumed one scoop (5 grams) of powdered zeolite and a urine collection test was performed as before (six hours timed, excluding first morning urine and while drinking two litters of water). For the secondary outcome, after the primary outcome observation period ended, all participants (Group A and Group B) were given the maximum recommended dose of the powdered zeolite preparation (Zeolite Pure by ZEO Health) of three scoops per day (15 grams) for total of four weeks to evaluate the safety of the product at the highest recommended dose. All participants were told to report any adverse events or symptoms during the trial. Participants received a blood test at the end of the four weeks to evaluate any potential impact of zeolite on blood chemistry, liver and/or kidney function values. Participants were not tested for excretion of heavy metals during the higher consumption of 15 grams of powdered zeolite.

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RESULTS Efficacy We tested the excretion in urine of the following twenty toxic elements: Arsenic, Lead, Mercury, Aluminum, Antimony, Barium, Bismuth, Cadmium, Cesium, Gadolinium, Gallium, Nickel, Niobium, Platinum, Rubidium, Thallium, Thorium, Tin, Tungsten and Uranium. We compared the levels of excretion at baseline (without the use of any zeolite preparations), to the excretion during the use of the zeolite preparations. We also observed the differences in excretion, between the participants who received the liquid preparations [either the oral drops (Natural Cellular Defense by Waiora) or the oral spray (ACZ Nano Extra Strength by Results RNA)], and when the same participants received the zeolite powdered preparation (Zeolite Pure by ZEO Health). We grouped the results of the oral spray and oral drops together in the same data set, since we did not observe any significant differences between the performances of either of the liquid preparations. For each participant, heavy metal, and different zeolite preparation, we calculated the percent difference (increase or decrease) in excretion by comparing the measured levels of the toxic metal in urine without any treatment (baseline) and during treatment with each zeolite preparation (chelating agent), i.e. we calculated the ratio of the difference in excretion divided by the levels of excretion before treatment. However, we note here that the closer the measured levels are to the detection limit, the less reliable the measurement because of different possible sources of variance. For example, a new small contamination from daily consumption of different vegetables can produce a slight increase, or even the standard deviation of the detection of the test can produce a small variance. This may lead to artificially high values of the aforementioned ratio due to low values in the denominator. Therefore, we apply a “cutoff” value on all measurements, such that after the application of the cutoff, no value can be below the cutoff. More formally, if x and y are the measured levels before and after treatment (respectively), and the cutoff is c, then we compute the following regularized ratio r: r = (max(y,c)-max(x,c))/max(x,c). For this trial, we chose the cutoff value to be the median excretion before treatment, across participants. The overall performance of each zeolite preparation per heavy metal across participants was measured in two ways: (a) median percent difference in excretion, and (b) percentage of participants that demonstrated a percent increase in excretion of at least 50% (the % significant in results). In Arsenic we observed a median increase in excretion of 119% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 73.7% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of -8% in the group that received the Emmanouil Karampahtsis NMD

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oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion. See Figure 1. Figure 1 - Arsenic Excretion at Baseline and During Consumption of Different Zeolite Preparations The graph below shows the results in urinary excretion of Arsenic. The yellow bar that is marked as “none” represents the excretion without any zeolite, at baseline. The maroon bar shows the excretion during the consumption of either the oral drops (Natural Cellular Defense by Waiora) or oral spray (ACZ Nano extra strength by Results RNA) zeolite preparation and marked as “other”; and the purple bar shows the urinary excretion of zeolite during the consumption of the powdered zeolite (Zeolite Pure by ZEO Health) preparation.

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In Aluminum we observed a median increase in excretion of 43% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 57.4% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion.

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In Antimony, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 5.3% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 10% of participants showing at least 50% increase in excretion. In Barium, we observed a median increase in excretion of 37% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 47.4% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 10% of participants showing at least 50% increase in excretion. In Bismuth, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 0% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion In Cadmium, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 10.5% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion. In Cesium, we observed a median increase in excretion of 41% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 31.6% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion. In Gadolinium, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 0% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion. In Gallium, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 15.8% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion.

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In Lead, we observed a median increase in excretion of 43% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 47.4% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion. In Mercury, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 5.3% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion. In Nickel, we observed a median increase in excretion of 23% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 26.3% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 10% of participants showing at least 50% increase in excretion. In Niobium, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 0% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 10% of participants showing at least 50% increase in excretion. In Platinum, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 5.3% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 10% of participants showing at least 50% increase in excretion. In Rubidium, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 0% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 10% of participants showing at least 50% increase in excretion. In Thallium, we observed a median increase in excretion of 119% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 73.7% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion.

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In Thorium, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 0% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion. In Tin, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 5.3% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 10% of participants showing at least 50% increase in excretion. In Tungsten, we observed a median increase in excretion of 99% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 68.4% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 10% of participants showing at least 50% increase in excretion. In Uranium, we observed a median increase in excretion of 0% in the powdered zeolite (Zeolite Pure by ZEO Health) group with 0% of participants showing at least 50% increase in excretion. We observed a median increase in excretion of 0% in the group that received the oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora) with 0% of participants showing at least 50% increase in excretion. A graph showing the percentage of participants that showed at least a 50% increase in excretion in the different metals, comparing the powdered to the liquid preparations performance can be seen in Figure 2. Of the twenty metals analyzed, fifteen have data represented on the graph. The powdered preparation is represented in fourteen of the fifteen metals present on the graph, whereas the liquid preparations are only represented in seven metals. This graph also demonstrates that the powdered preparation outperformed the liquid preparations by a ratio of 11:4.

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Figure 2 - Percentage of Participants with at Least 50% Increase in Excretion The comparison of the percent of participants that showed at least a 50% increase in excretion of different heavy metals during consumption of the powdered zeolite preparation (Zeolite Pure by ZEO Health) or the liquid zeolite preparation [oral drops (Natural Cellular Defense by Waiora) or oral spray (ACZ Nano extra strength by Results RNA)] (marked as “other”). 100% 90% 80% 70% 60% 50% 40% 30% 20% 10%

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0%

Other

The comparison of the median excretion of different metals across participants during the consumption of the zeolite preparations can be seen in Figure 3. The powdered preparation (Zeolite Pure by ZEO Health) shows positive results for eight of the twenty metals. The liquid preparations [ACZ (Advanced Cellular Zeolite) Nano Extra Strength by Results RNA or Natural Cellular Defense by Waiora] are represented on the graph for only one metal, in the negative region. This graph demonstrates that the median excretion was higher for the powdered preparation in all nine of the metals that evidence appears for on the graph.

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Figure 3 - Median Increase in Excretion Across Participants per Heavy Metal The comparison of the median excretion of different metals across participants during consumption of the powdered zeolite preparation (Zeolite Pure by ZEO Health) or the liquid zeolite preparation [oral drops (Natural Cellular Defense by Waiora) or oral spray (ACZ Nano extra strength by Results RNA)] (marked as “other”). 120%

100%

80%

60%

40%

20%

0%

Powdered Zeolite

Uranium

Tungsten

Tin

Thorium

Thallium

Rubidium

Platinum

Niobium

Nickel

Mercury

Lead

Gallium

Gadolinium

Cesium

Cadmium

Bismuth

Barium

Arsenic

Antimony

Aluminum

-20%

Other

Safety All participants tolerated the zeolite preparations very well. One participant reported flatulence with the consumption of three scoops (15 grams) of the powdered zeolite preparation (Zeolite Pure by ZEO Health) which was relieved immediately when dose was lowered to two scoops (10 grams) per day. No other participants reported any adverse reactions or symptoms. Comparison of the blood tests pre-consumption of zeolite and post-consumption of zeolite showed no difference in any of the measured values. No negative effects on the blood work were seen. No significant changes were observed in kidney function [BUN (blood urea Emmanouil Karampahtsis NMD

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nitrogen), Creatinine, GFR (Glomerular Filtration Rate) calculated], liver function [AST (aspartate transaminase) and ALT (alanine transaminase)] or electrolyte levels (sodium, potassium, chloride) immediately after the consumption of each of the zeolite preparations. This proves our hypothesis that zeolite is a safe product for oral consumption. ____________________________________________________________________________________

DISCUSSION We observed the most urinary excretion with the use of the powdered zeolite preparation (Zeolite Pure by ZEO Health) as an oral chelating agent in the following heavy metals (mean percent increase in excretion): Arsenic 119%, Thallium 119%, Tungsten 99%, Lead 43%, Aluminum 43%, Cesium 41%, Barium 37% and Nickel 23%. The percent of significance in results, people that showed at least a 50% increase in excretion of the heavy metal during the consumption of the powdered zeolite preparation, in comparison to baseline, were as follows: Arsenic 73.7%, Thallium 73.7%, Aluminum 57.4%, Tungsten 68.4%, Lead 47.4%, Barium 47.4%, Cesium 31.6%, and Nickel 26.3%. We believe that these results are statistically significant to show that the powdered zeolite preparation (Zeolite Pure by ZEO Health) works as an oral chelating agent at least for those metals that showed an increase in urinary excretion by more than 50%. In those heavy metals that we did not observe any excretion, either at baseline (without the use of any zeolite preparation) or during the ingestion of zeolite, it is worth mentioning that 0% excretion does not necessarily mean that the zeolite has no affinity for those metals. Due to the small number of participants, these results probably indicate the absence of those metals in the body of the participants. We also observed, in some metals, higher excretion numbers at baseline in comparison to the excretion during consumption of zeolite. This created negative values that resulted in the mean percent of excretion to be zero, even though some participants did have higher excretion rates of that metal during the consumption of zeolite. Without being able to analyze any further, we can look for probable causes or variables that might have played a role in this situation. One simple explanation is a possible recent exposure to the metal during the measurement at baseline. Since we controlled for all seafood consumption, the exposure could be from a different food or water source. Since the participants were placed on zeolite oral treatment for five days prior to a second measurement, it is possible for the zeolite to clear the metal from the body that was recently exposed; therefore, the second test could show a lower value. We observed that this happened with metals with low excretion at baseline, close to the detection limit. In our trial we used, for those participants that consumed the oral drops (Natural Cellular Defense by Waiora) or oral spray (ACZ Nano Extra Strength by Results RNA), the higher daily dose recommended by the company and listed on their respective websites. For the powdered

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zeolite preparation (Zeolite Pure by ZEO Health), we used the minimum recommended dose from the company of one scoop (5 grams) per day. Since the maximum recommended daily dose of the powdered zeolite preparation is three scoops per day (15 grams), it is possible that for those toxic metals that we did not observe any significant excretion with the use of this product could also be dose dependent. A higher dose of two or three scoops per day could have shown an increase in urinary excretion of those metals. Nevertheless, the obtained results showed the superiority of the powdered zeolite preparation, even at the lowest dose, in comparison to the other preparations taken at their higher doses. All twenty participants, at the second part of the trial, (after all urine measurements for the excretion of heavy metals, with the use of any zeolite preparation, were competed), consumed the maximum recommended dose (15 grams per day) of the powdered zeolite preparation (Zeolite Pure by ZEO Health), for four weeks. No major symptoms were reported with the higher dose and no negative changes were recorded in their blood tests. It was during this portion of the trial that the one participant reported flatulence. No other participants reported any other adverse side effects. This shows that this specific zeolite preparation (Zeolite Pure by ZEO Health) is also safe to be consumed for four weeks at the maximum dose of three scoops per day, which is equal to 15 grams. One of the major concerns with most chelating agents, such as DMPS (2,3-dimercapto-1propanesulfonic acid) and DMSA (dimercaptosuccinic acid), is their effects on kidney function as the toxic elements exit the body during urination. In our participants, we observed no differences in the blood measurements of BUN and Creatinine, as well as the calculated values of GFR at baseline and immediately after the consumption of zeolite at the end of the trial. Group B was followed with a blood test immediately after the completion of the six days on either of the liquid preparations [oral spray (ACZ Nano Extra Strength by Results RNA) or oral drops (Natural Cellular Defense by Waiora)] to check for any kidney function abnormalities. No differences were found between baseline and post-consumption of the products. Thus, we can conclude that the specific liquid preparations tested are safe at the higher recommended doses, and do not cause any additional burden on kidney function. We have examined the toxicology study performed with the Zeolite Pure powdered preparation (by ZEO Health) by MB Research Laboratories on Sprague Dawley rats prior to this trial. According to their results, the LD50 (lethal dose) of Zeolite Pure powdered preparation (by ZEO Health) is greater than 5000mg/kg of body weight in male rats, which makes it a non-toxic substance as defined in 16 CFR (Code of Federal Regulations) 1500.3(c)(2)(1) of the Federal Hazardous Substances Act. It is important to report the safety of these products as it showed from our findings in all of our twenty human participants in this trial. No changes in the complete blood count were observed that could signify any negative results imposed from the consumption of the product to the participants. No changes in liver enzymes AST and ALT were observed to signify any negative Emmanouil Karampahtsis NMD

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or toxic effects in the liver. No changes were observed in the electrolytes at the comprehensive metabolic profile analysis to signify any negative effects of the product on the blood chemistry of the participants. Those results prove our hypothesis that at least the tested zeolite preparations are safe for human consumption at the recommended doses. These results also add to the general body of knowledge that zeolite can be safely consumed as an oral supplement for detoxification and chelation purposes. Since the excretion of the toxic metals during the consumption of the three zeolite preparations tested was so different, we propose that the effectiveness of the zeolite as an oral chelating agent is product and/or dose specific. It is also important to mention that of all three zeolite preparations tested, the powdered zeolite preparation (Zeolite Pure by ZEO Health), at its minimum dose, was the one preparation that provided the largest amount of zeolite per serving. It is possible to extrapolate or at least raise the question, that the effectiveness of zeolite as an oral chelating agent is dose dependent, and further studies are needed to evaluate dosing and effectiveness among other types of zeolite preparations on the market, such as drops, sprays, capsules and powders. One of the limitations of the trial is the small number of participants. With a greater number of participants, the group might have been a better representation of the general population. We anticipate that the results might have been slightly different, since a larger group would increase the probability of having a number of participants with elevated levels of those toxic metals that we were not able to observe any excretion in our smaller trial group. A second limitation identified was the selection of the participants. We selected our participants randomly, instead of pre-screening them for the presence of heavy metal toxicity, with the use of another already widely approved chelating agent, such as DMSA. This would have served as a control in that the participants would have had an existing burden of toxic metals present in their body prior to the trial. Moreover it would have provided a comparison of the effectiveness of zeolite versus another widely used chelating agent. Our hypothesis has been confirmed. We observed the fact that results were dependent on the preparation and that they were not equal among all of the zeolite preparations tested. The question that arises, which requires follow up research, is to compare the effectiveness of zeolite as an oral chelating agent with another oral chelating agent that has been used for years, such as DMSA. Further studies need be performed to compare zeolite with other known chelating agents and to compare different doses as to establish data for the most effective dose of this substance. This follow up comparison would show the strengths as to which specific heavy and potentially toxic metals the zeolite has more affinity for in comparison to the other chelating agent. This comparison would also provide more clinical guidance as to the use of the most effective chelating agent for the removal of specific toxic metals present in the human body.

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____________________________________________________________________________________

CONCLUSIONS This study was able to provide data that zeolite in all three different preparations tested proved to be a safe substance for human consumption. The powdered zeolite preparation (Zeolite Pure by ZEO Health) has shown to be an effective oral chelation agent for detoxification of several toxic metals. When properly prepared as an oral supplement, zeolite can provide support to the human body to rid itself of heavy and toxic metals with minimal or no side effects. The use of zeolite can be used in cases of lead, mercury or radiation poisoning to remove the harmful metals without further taxing the body. ____________________________________________________________________________________

List of Abbreviations ACZ - Advanced Cellular Zeolite; ALT - Alanine transaminase; AST - Aspartate transaminase; BUN - Blood urea nitrogen; CFR - Code of Federal Regulations; DMPS - 2,3-Dimercapto-1propanesulfonic acid; DMSA - Dimercaptosuccinic acid; FDA - Federal Drug Administration; GFR - Glomerular Filtration Rate; GRAS - Generally Recognized As Safe; LD - Lethal Dose; NMD - Doctor of Naturopathic Medicine. ____________________________________________________________________________________

Authors' Information Dr. Emmanouil Karampahtsis is Board Certified in Antiaging Medicine and an active member of the American Academy of Antiaging Medicine. He graduated with honors from the Honors College at Adelphi University in Garden City, NY, in 1998 with a bachelor’s degree in Psychology. Immediately following, he was accepted at the Southwest College of Naturopathic Medicine in Tempe, AZ, where he graduated with the degree of Doctor of Naturopathic Medicine in 2003. After passing his national board exams and receiving his license in 2004, he started his private practice in Scottsdale Arizona, and has maintained it ever since. Dr. Karampahtsis has treated many patients with different ailments, and has experience utilizing many different naturopathic and pharmaceutical approaches in healing. He has seen success treating people with many chronic diseases when the toxic metals were addressed. The results made him interested in searching for the most effective and the least invasive chelating and detoxification methods to rid the body of toxic, heavy metals. ____________________________________________________________________________________

Acknowledgements The author would like to publicly thank the participants for their cooperation in the trial, since they were not compensated for their participation.

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REFERENCES Babel S, Kurniawan TA. Low-cost adsorbents for heavy metals uptake from contaminated water: a review. J Hazard Mater. 2003;97(1-3):219-43. Baker HM, Massadeh AM, Younes HA. Natural Jordanian zeolite: removal of heavy metal ions from water samples using column and batch methods. Environ Monit Assess. 2009;157(14):319-30. Flowers JL, Lonky SA, Deitsch EJ. Clinical evidence supporting the use of an activated clinoptilolite suspension as an agent to increase urinary excretion of toxic heavy metals. Nutrition and Dietary Supplements. 2009, 1:11-18. Available from: Dove Press, Article ID 3696. Förstner U, Jacobs P, Kammer F. Impact of natural nanophases on heavy-metal retention in zeolite-supported reactive filtration facilities for urban run-off treatment. Fresenius J Anal Chem. 2001;371(5):652-9. Sprynskyy M. Solid-liquid-solid extraction of heavy metals (Cr, Cu, Cd, Ni and Pb) in aqueous systems of zeolite-sewage sludge. J Hazard Mater. 2009;161(2-3):1377-83.

© Copyright 2012 by Emmanouil Karampahtsis – All Rights Reserved This study, and/or the information contained herein, is not intended to treat, diagnose or cure any medical conditions. These statements have not been evaluated by the Food and Drug Administration. This study is presented for educational purposes and is therefore supplementary and not to be considered exhaustive. This study may not be copied in whole or in part (electronic, photocopying, recording, or otherwise) without the written consent of Emmanouil Karampahtsis. This publication is protected under the US Copyright Act of 1976 and all other applicable international, federal, state and local laws, and all rights are reserved, including resale rights. Violators will be prosecuted to the fullest extent of the law. Any trademarks, service marks, product names or named features are assumed to be the property of their respective owners, and are used only for reference. There is no implied endorsement if we use one of these terms.

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